Firing patterns of neurons

1   The spontaneous activity of Purkinje cells

1.1     Record the spontaneous activity of a Purkinje cell

1.2     Characterize the currents underlying the spontaneous action potentials

1.3     Characterize the subliminar current that allows the spontaneous depolarization of the membrane to the threshold of action potentials

2   The two discharge modes of thalamic [or subthalamic] neurons

2.1     Record the two discharge modes of thalamic neurons according to membrane potential

2.2     Characterize the currents responsible for the action potentials of each mode

2.3     Characterize in voltage clamp mode the subliminar voltage-gated currents present in the neuronal membrane. Show in which mode they are playing a role.