Action potential propagation in myelinated and unmyelinated axons.
The AxonLab component serves to set parameters of the environment and recording system. Properties of the axon to be studied are in the Axon object.
This component is responsible for running the calculation (click the run button). The results are displayed in a standard image display labelled v_history. The temperature, solution and axon and stimulus fields govern the model being studied. The other fields concern the numerical method and discretization.
The following fields can be set here:
| temperature | the temperature to be used in computing channel transition rates |
| solution | the external solution bathing the axon |
| axon | the particular axon model to use |
| max_N_stochastic | the number of channels beyond which stochastic effects are ignored. That is, up to this number at a singoe site, each channel is computed seperately. Above this numbe an ensemble average is taken |
| vmin | minimum potential for the voltage discretization |
| vmax | maximum potential for the voltage discretization |
| nv | number of discrete voltages used in the calculation. If this is to small, discretization effects may be seen, if too large, it slows down the calculation. 100 is usually pretty safe. |
| discDeltaL | discretization length for uniform sections of axon |
| timestep | fixed timestep for the calculation, ms |
| sampleInterval | time interval at which to record the potential making this larger than the timestep can be useful to reduce the size of the output data arrays so they can be manipulated more easily |
| gatingCurrents | select whether to include gating currents in the calculation |
| stimProtocol | if set, the stimulus to give at the start of the axon |
| profile | an alternative way of specifiing the stimulus, rather than using hte stimProtocol - profiles are more flexible, but also more complicated. |
| recA | a display of the voltage history at the beginning, where the stimulus is applied |
| rerun | select whether to rerun the calculation whenever a parameter is changed, or only when requested with the "run" button |
| v_history | a 2-D display of the voltage as a function of position and time |