HHGate

A voltage dependent gate for channels following the Hodgkin-Huxley formalism. The equivalent gating charge is z, half potential, Vhalf (mV), and gating asymmetry gamma: 0 < gamma < 1. The transition rates are expressed through their reciprocals, the characteristic timescales, tau-x near Vhalf, and tau-m (tau-m << tau-x), the saturation timescale for extreme potentials. The power gives the number of repeats of this gate on a channel: the power to which the gating variable is raised in calculating the channel conductance.

The gating is computed from the forward and reverse rates, alpha and beta, given by:

private final double alpha (double v) {
double a = Math.exp (ebykt * (gamma) * z * (v - Vhalf)) / tau_x;
a = 1. / (1. / a + tau_m);
return a;
}

private final double beta (double v) {
double b = Math.exp (-ebykt * (1. - gamma) * z * (v - Vhalf)) / tau_x;
b = 1. / (1. / b + tau_m);
return b;
}

field	type	contents / default value
Vhalf	double	-40.0	variable: Vhalf type: double
z	double	1.0	variable: z type: double
tau_x	double	10.0	variable: tau_x type: double
tau_m	double	1.0	variable: tau_m type: double
gamma	double	0.5	variable: gamma type: double
power	integer	2	variable: power type: integer
HHGate-results	object	CalcResults